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Debt offeringSEC filing

Aptevo files prospectus supplement for up to $2,309,834 ATM common-stock offering

On October 30, 2026, Aptevo Therapeutics filed a prospectus supplement under its effective Form S-3 registration statement to sell common stock from time to time with an aggregate offering price of up to $2,309,834 under an existing ATM Sales Agreement. Roth Capital Partners, LLC is the sales agent, and the company reported that it had issued and sold 303,157 shares under the Sales Agreement and Prior Prospectus for $11.8 million in aggregate gross proceeds as of the prospectus supplement date.

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Company updateOfficial company source

Mipletamig Combination: 21% of Evaluable Frontline AML Patients Proceeded to Transplant

Aptevo reported that 10 of 47 evaluable frontline AML patients treated with mipletamig plus venetoclax and azacitidine proceeded to allogeneic stem cell transplantation (21%). Nine patients came from the ongoing Phase 1b RAINIER trial and one from a completed dose expansion trial; the release also cited 3 of 286 patients (0.7%) undergoing transplantation after VEN+AZA alone in the historical VIALE-A trial and stated that cross-trial comparisons are limited. Aptevo expects RAINIER dose optimization to conclude by...

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